Key result
Aging leads to functional and structural changes in the cardiovascular system, such as decreased cardiac output and increased arterial stiffness, which predispose older adults to cardiovascular diseases.
Why the study?
Many changes occur in the cardiovascular system with aging that predispose to diseases, prompting an examination of the physiological relationship between aging and cardiovascular diseases.
Aging is an inevitable risk factor for cardiovascular diseases, causing physiological changes such as decreased cardiac output, increased arterial stiffness, and higher systolic blood pressure.
Supports age-specific CV monitoring in practice; leaves open targeted intervention trials in prospective cohorts.
According to the World Health Organization, the term “elderly” refers to people over the age of 65. Decreases in heart rate, heart function, oxygen consumption and stroke rate occur with aging. Many changes occur in the cardiovascular system with aging, and this predisposes to diseases. The aim of this review article is to examine the physiological relationship between aging and cardiovascular diseases. Depending on genetic differences and age, the heart's ability to pump blood decreases, the myocardium loses flexibility, and the heart valves thicken and increase in diameter. Aging is an inevitable part of life and constitutes the most important risk factor for cardiovascular diseases. Arteriosclerosis increases the thickness of blood vessels while decreasing their elasticity. Functional and structural changes in the cardiovascular system in older ages increase the risk of coronary artery disease, heart diseases, heart failure, venous thrombosis, and hypertension. Cardiac output and stroke volume decreases and the risk of postural hypotension increases. With advancing age, a continuous rise in systolic blood pressure occurs as a result of a hardening of the vessels and their diminished elasticity. After the age of 60, either a slight decrease or no change is seen in diastolic blood pressure.
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Topuz et al. (2024) conducted a review in Cardiovascular diseases. Aging was evaluated. Aging leads to functional and structural changes in the cardiovascular system, such as decreased cardiac output and increased arterial stiffness, which predispose older adults to cardiovascular diseases.
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