Key result
Advancing calendar years from 2001 to 2014 were associated with a 2.6% annual decline in incident acute myocardial infarction in men (IRR 0.974) and 2.8% in women (IRR 0.972).
Observational (n=221,684)
Relative Risk: 0.974 (95% CI 0.972–0.977)
Incident acute myocardial infarction rates in Norway continued to decline from 2001 to 2014 across all age groups, notably including a new decline among younger adults aged 25-44 years.
Continued AMI incidence decline in Norway now includes ages 25–44; extends prior trends but leaves generalizability open.
Background We updated the information on trends of incident acute myocardial infarction in Norway, focusing on whether the observed trends during 2001-2009 continued throughout 2014. Methods All incident (first) acute myocardial infarctions in Norwegian residents age 25 years and older were identified in the Cardiovascular Disease in Norway 1994-2014 project. We analysed overall and age group-specific (25-64 years, 65-84 years and 85 + years) trends by gender using Poisson regression analyses and report the average annual changes in rates with their 95% confidence intervals. Results During 2001-2014, 221,684 incident acute myocardial infarctions (59.4% men) were identified. Hospitalised cases accounted for 79.9% of all incident acute myocardial infarctions. Overall, incident acute myocardial infarction rates declined on average 2.6% per year (incidence rate ratio 0.974, 95% confidence interval 0.972-0.977) in men and 2.8% per year (incidence rate ratio 0.972, 95% confidence interval 0.971-0.974) in women, contributed by declining rates of hospitalisations (1.8% and 1.9% per year in men and women, respectively) and deaths (6.0% and 5.8% per year in men and women, respectively). Declining rates were observed in all three age groups. The overall acute myocardial infarction incidence rates continued to decline from 2009 onwards, with a steeper decline compared to 2001-2009. During 2009-2014, gender-adjusted acute myocardial infarction incidence among adults age 25-44 years declined 5.3% per year, contributed mostly by declines in hospitalisation rates (5.1% per year). Conclusion Acute myocardial infarction incidence rates continued to decline after 2009 in Norway in both men and women. The decline started to involve individuals aged 25-44 years, marking a turning point in the previously reported stagnation of rates during 2001-2009.
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Sulo et al. (2018) conducted an observational in Acute myocardial infarction (n=221,684). Calendar year was evaluated on Annual change in incident acute myocardial infarction rates (men) (IRR 0.974, 95% CI 0.972-0.977). Advancing calendar years from 2001 to 2014 were associated with a 2.6% annual decline in incident acute myocardial infarction in men (IRR 0.974) and 2.8% in women (IRR 0.972).
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