Key result
Age over 60 years (OR 1.31; 95% CI 1.11-1.55), irregular physical activity, and low medication adherence were associated with uncontrolled blood pressure in hypertensive Brazilians.
Why the study?
Uncontrolled hypertension has a high prevalence and is related to numerous negative health outcomes, motivating an investigation into factors associated with uncontrolled blood pressure in hypertensive Brazilians.
Cross-Sectional (n=2,643)
Yes
Odds Ratio: 1.31 (95% CI 1.11–1.55)
In a large Brazilian cohort, nearly half of hypertensive patients had uncontrolled blood pressure, with poor control associated with typical cardiovascular risk factors and better control paradoxically seen in those with established atherosclerotic disease.
Identifies modifiable risks tied to uncontrolled BP in treated patients; leaves open whether intervening on them improves control in similar populations.
Uncontrolled hypertension has a high prevalence and is related to numerous negative health outcomes. This study aimed to investigate the factors associated with the lack of blood pressure control in hypertensive Brazilians treated in public and private services. This is an analytical, multicentric, and national cross-sectional study, carried out with adult hypertensive patients, monitored in 45 outpatient clinics (September 2013 to October 2015) in a prospective record interview, clinical, and anthropometric assessment. Outcome variables included uncontrolled pressure (systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg). Simple and multiple logistic regression analyses were performed. Two thousand six hundred forty-three participants were assessed with a mean age of 61.6 ± 11.9 years, 55.7% of women, and 46.4% with uncontrolled blood pressure (BP). The following were associated with uncontrolled BP: age over 60 years (OR: 1.31 [1.11-1.55]); practice of irregular physical activity (OR: 1.28 [1.06-1.55]); attending the emergency room for hypertensive crises in the last six months (OR: 1.80 [1.46-2.22]); increased body mass index (OR: 1.02 [1.01-1.04]); low adherence to drug treatment (OR: 1.22 [1.04-1.44]) and menopause (OR: 1.36 [1.07-1.72]). The following were negatively associated: fruit consumption (OR: 0.90 [0.85-0.94]); presence of dyslipidemia (OR: 0.75 [0.64-0.89]), acute myocardial infarction (OR: 0.59 [0.46-0.76]), and peripheral arterial disease (OR: 0.52 [0.34-0.78]). Factors associated with difficult-to-control blood pressure are the same that increase the risk for hypertension, while the presence of atherosclerotic disease and its outcomes were associated with better control.
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Araújo et al. (2022) conducted a cross-sectional in Hypertension (n=2,643). Age over 60 years vs. Age 60 years or younger was evaluated on Uncontrolled blood pressure (systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg) (OR 1.31, 95% CI 1.11-1.55). Age over 60 years (OR 1.31; 95% CI 1.11-1.55), irregular physical activity, and low medication adherence were associated with uncontrolled blood pressure in hypertensive Brazilians.
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