Key result
An intraoperative type A response had a negative predictive value of 0.97 for a postoperative type C response, suggesting approximately 90% of patients can be discharged without postoperative testing.
Why the study?
Does intraoperative ICD testing response predict the need for postoperative predischarge testing in patients undergoing ICD implantation?
Cohort (n=211)
Does intraoperative ICD testing response predict the need for postoperative predischarge testing in patients undergoing ICD implantation?
An intraoperative defibrillation safety margin ≥10 J at ≤20 J absolute energy reliably predicts successful postoperative ICD function, potentially eliminating the need for predischarge testing in ~90% of patients.
Answers are grounded in this paper and cite their sources.
Should not yet alter predischarge testing protocols; leaves open whether intraoperative responses can safely guide selective testing in prospective cohorts.
The results of intraoperative and postoperative predischarge implantable cardioverter-defibrillator (ICD) testing of 211 consecutive patients, starting at 15 J and requiring two successful terminations of induced VT/VF with a relative defibrillation safety margin (DSM) of >10 J, were reviewed. The aim was to define the type of intraoperative response that would make postoperative predischarge testing unnecessary. The intraoperative responses were divided into three types: A, a DSM > or =10 J and an absolute energy level of < or =20 J; B, a DSM of > or =10 J and an absolute energy level of >20 J; and C, a DSM <10 J and an absolute energy level of >20 J. At operation, the responses to defibrillation were A, 88.6%; B, 7.1%; and C, 4.3%. Accepting an A response only would leave 11.4% of the patients for postoperative testing. The positive and negative predictive values for diagnosing a postoperative C response were 0.78 and 0.97, respectively. Similarly, the predictive values for diagnosing a postoperative B or C response were 0.71 and 0.97, respectively. The postoperative testing responses were A, 89.1%; B, 4.3%; and C, 6.6%. In summary, an intraoperative A response was sufficient to make a postoperative defibrillation testing unnecessary, while it was found that intraoperative B and C responders should undergo postoperative testing. Applying these criteria, approximately 90% of the patients could be discharged without any postoperative induction test.
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Sandstedt et al. (2007) conducted a cohort in Patients undergoing implantable cardioverter-defibrillator (ICD) implantation (n=211). Intraoperative ICD testing response vs. Postoperative predischarge testing was evaluated on Postoperative type C response (defibrillation safety margin <10 J and absolute energy >20 J). An intraoperative type A response had a negative predictive value of 0.97 for a postoperative type C response, suggesting approximately 90% of patients can be discharged without postoperative testing.
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