What does this research mean for the field?

Dual primary malignancies are increasingly detected among cancer survivors, with metachronous lesions being more common than synchronous ones, necessitating vigilant long-term screening and follow-up. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe the clinical characteristics, tumor profiles, and treatment patterns of patients diagnosed with dual primary malignancies.

September 5, 2026South Asian Journal of CancerOpen Access

Dual primary malignancies are no longer a rarity: A single centre experience from eastern India

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Authors

SSSantosh Kumar Swain LMLalatendu Moharana SSSudam Sadangi

Discussion

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Overview

Retrospective study observes frequent metachronous presentations in patients with dual primary malignancies, highlighting the need for vigilant long-term surveillance.

Key Points

To describe the clinical characteristics, tumor profiles, and treatment patterns of patients diagnosed with dual primary malignancies.
Retrospective review of prospectively maintained records (January 2023 to December 2024) of N=21 patients with histologically confirmed dual primary malignancies at a single center in eastern India.
Tumors were classified into synchronous and metachronous types according to the Warren and Gates criteria alongside demographic and anatomical site evaluations.
Among the 21 patients (57.1% male, 42.9% female), 61.9% (n=13) were metachronous and 38.1% (n=8) were synchronous lesions.
First primary tumors predominantly involved the breast, colon, head and neck, rectum, and prostate, whereas second primary tumors most commonly arose in the thyroid (notably papillary carcinoma), breast (28.6% overall, n=6), gastrointestinal tract, and prostate.

Cite This Study

Swain et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd3f16b95aff0620eb28d https://doi.org/10.25259/sajc_67_2025

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September 5, 2026South Asian Journal of CancerOpen Access

Dual primary malignancies are no longer a rarity: A single centre experience from eastern India

View Full Paper

Ask AI

Bookmark

Authors

SSSantosh Kumar Swain LMLalatendu Moharana SSSudam Sadangi

Discussion

Member takes

Overview

Retrospective study observes frequent metachronous presentations in patients with dual primary malignancies, highlighting the need for vigilant long-term surveillance.

Key Points

To describe the clinical characteristics, tumor profiles, and treatment patterns of patients diagnosed with dual primary malignancies.
Retrospective review of prospectively maintained records (January 2023 to December 2024) of N=21 patients with histologically confirmed dual primary malignancies at a single center in eastern India.
Tumors were classified into synchronous and metachronous types according to the Warren and Gates criteria alongside demographic and anatomical site evaluations.
Among the 21 patients (57.1% male, 42.9% female), 61.9% (n=13) were metachronous and 38.1% (n=8) were synchronous lesions.
First primary tumors predominantly involved the breast, colon, head and neck, rectum, and prostate, whereas second primary tumors most commonly arose in the thyroid (notably papillary carcinoma), breast (28.6% overall, n=6), gastrointestinal tract, and prostate.

Cite This Study

Swain et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd3f16b95aff0620eb28d https://doi.org/10.25259/sajc_67_2025

Also Consider

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