What does this research mean for the field?

Patient factors including darker skin types, older age, higher BMI, diabetes, and hypertension, along with film-only dressings, significantly increase the risk of donor site dyspigmentation and hypertrophic scarring following split-thickness skin grafts, whereas calcium alginate and silver dressings reduce this risk. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

Identify patient demographics, clinical comorbidities, and wound dressing types associated with donor site hypertrophic scarring and dyspigmentation following split-thickness skin graft procedures.

September 5, 2026Journal of Burn Care & Research

Donor Site Scarring and Dyspigmentation Following Split-Thickness Skin Graft Procedure: A Large-Sample, Single-Site Retrospective Study

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Authors

SHSakura Helm SBSigrid A Blome-Eberwein

Discussion

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Overview

Retrospective study identifies risk factors for donor site scarring and dyspigmentation after skin grafting, highlighting a need for individualized wound care.

Key Points

Identify patient demographics, clinical comorbidities, and wound dressing types associated with donor site hypertrophic scarring and dyspigmentation following split-thickness skin graft procedures.
Retrospective review of 1,021 patients who underwent split-thickness skin grafting at a regional burn center between 2015 and 2024.
Analyzed clinical and follow-up data from 559 patients with documented donor site appearances to assess associations with patient demographics, comorbidities, graft thickness, healing time, and dressing types.
Fitzpatrick skin types IV, V, and VI accounted for 46.6% of patients presenting with hypertrophic features despite comprising only 14.7% of the cohort (P < .001).
Older age (OR = 1.017 per year, P < .001), BMI ≥ 25 (OR = 2.00, P < .001), hypertension alone (OR = 1.92, P < .001), and combined diabetes with hypertension (OR = 2.71, P < .001) significantly increased dyspigmentation odds.
Calcium alginate and silver dressings lowered dyspigmentation odds (OR = 0.368, P < .001), whereas film-only dressings increased risk (OR = 2.31, P < .001); graft thickness and healing time showed no statistically significant effect.

Cite This Study

Helm et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd3f16b95aff0620eb31f https://doi.org/10.1093/jbcr/irag158

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September 5, 2026Journal of Burn Care & Research

Donor Site Scarring and Dyspigmentation Following Split-Thickness Skin Graft Procedure: A Large-Sample, Single-Site Retrospective Study

View Full Paper

Ask AI

Bookmark

Authors

SHSakura Helm SBSigrid A Blome-Eberwein

Discussion

Member takes

Overview

Retrospective study identifies risk factors for donor site scarring and dyspigmentation after skin grafting, highlighting a need for individualized wound care.

Key Points

Identify patient demographics, clinical comorbidities, and wound dressing types associated with donor site hypertrophic scarring and dyspigmentation following split-thickness skin graft procedures.
Retrospective review of 1,021 patients who underwent split-thickness skin grafting at a regional burn center between 2015 and 2024.
Analyzed clinical and follow-up data from 559 patients with documented donor site appearances to assess associations with patient demographics, comorbidities, graft thickness, healing time, and dressing types.
Fitzpatrick skin types IV, V, and VI accounted for 46.6% of patients presenting with hypertrophic features despite comprising only 14.7% of the cohort (P < .001).
Older age (OR = 1.017 per year, P < .001), BMI ≥ 25 (OR = 2.00, P < .001), hypertension alone (OR = 1.92, P < .001), and combined diabetes with hypertension (OR = 2.71, P < .001) significantly increased dyspigmentation odds.
Calcium alginate and silver dressings lowered dyspigmentation odds (OR = 0.368, P < .001), whereas film-only dressings increased risk (OR = 2.31, P < .001); graft thickness and healing time showed no statistically significant effect.

Cite This Study

Helm et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd3f16b95aff0620eb31f https://doi.org/10.1093/jbcr/irag158

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