What does this research mean for the field?

In patients with gastrointestinal stromal tumors, high mitotic index and lymph node metastasis are associated with disease progression, and curative surgery improves survival, whereas tumor size, location, and stage are not associated with progression. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the demographic, clinical, and pathological features, prognostic risk factors, treatments, and survival outcomes of patients diagnosed with gastrointestinal stromal tumors.

September 5, 2026Uludağ Üniversitesi Tıp Fakültesi DergisiOpen Access

Retrospective Evaluation of Demographic and Clinical Features of Gastrointestinal Stromal Tumors

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Authors

NÇNihal Yücel Çamci NUNesrin Uğraş ADAdem Deligönül

Discussion

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Overview

Retrospective study reveals clinical predictors of survival in patients with gastrointestinal stromal tumors, highlighting curative surgery and mitotic index as key prognostic factors.

Key Points

To evaluate the demographic, clinical, and pathological features, prognostic risk factors, treatments, and survival outcomes of patients diagnosed with gastrointestinal stromal tumors.
Retrospective medical record review of N=54 patients diagnosed with gastrointestinal stromal tumors between 2002 and 2017 at Bursa Uludağ University Faculty of Medicine in Bursa, Turkey.
The cohort had a mean age of 56.15 ± 10.68 years with 63.0% (n=34) male predominance; primary tumor sites were predominantly the small intestine (40.7%, n=22) and stomach (35.2%, n=19), with CD117 (C-KIT) positivity in 94.4% (n=51).
Curative surgical resection was associated with longer survival times, while high mitotic index and lymph node metastasis significantly correlated with disease progression; tumor size, anatomical location, and clinical stage showed no association with progression.

Cite This Study

Çamci et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd4536b95aff0620ebf92 https://doi.org/10.32708/uutfd.1864352

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September 5, 2026Uludağ Üniversitesi Tıp Fakültesi DergisiOpen Access

Retrospective Evaluation of Demographic and Clinical Features of Gastrointestinal Stromal Tumors

View Full Paper

Ask AI

Bookmark

Authors

NÇNihal Yücel Çamci NUNesrin Uğraş ADAdem Deligönül

Discussion

Member takes

Overview

Retrospective study reveals clinical predictors of survival in patients with gastrointestinal stromal tumors, highlighting curative surgery and mitotic index as key prognostic factors.

Key Points

To evaluate the demographic, clinical, and pathological features, prognostic risk factors, treatments, and survival outcomes of patients diagnosed with gastrointestinal stromal tumors.
Retrospective medical record review of N=54 patients diagnosed with gastrointestinal stromal tumors between 2002 and 2017 at Bursa Uludağ University Faculty of Medicine in Bursa, Turkey.
The cohort had a mean age of 56.15 ± 10.68 years with 63.0% (n=34) male predominance; primary tumor sites were predominantly the small intestine (40.7%, n=22) and stomach (35.2%, n=19), with CD117 (C-KIT) positivity in 94.4% (n=51).
Curative surgical resection was associated with longer survival times, while high mitotic index and lymph node metastasis significantly correlated with disease progression; tumor size, anatomical location, and clinical stage showed no association with progression.

Cite This Study

Çamci et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd4536b95aff0620ebf92 https://doi.org/10.32708/uutfd.1864352

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