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June 29, 2022Journal of Clinical MedicineOpen Access

Associations between Heart Rate Variability Parameters and Hemodynamic Profiles in Patients with Primary Arterial Hypertension, Including Antihypertensive Treatment Effects

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Key result

Heart rate variability parameters of increased autonomic nervous system activity correlated with improved left ventricle function and lower left ventricular afterload.

Why the study?

Autonomic nervous system dysfunction is an important factor in arterial hypertension and may produce adverse hemodynamic sequelae.

Does antihypertensive treatment improve heart rate variability and hemodynamic profiles in patients with primary arterial hypertension?

Population

144 patients with uncomplicated AH

Comparison

Antihypertensive treatment effects after 12 months

Follow-up

12 months

Authors

MMMałgorzata MaciorowskaNational Academy of MedicinePKPaweł KrzesińskiGeneral CardiologyRWRobert WierzbowskiNational Academy of Medicine

Discussion

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Member takes

Overview

Association of HRV with LV function supports autonomic monitoring in hypertension; hypothesis-generating without causal evidence.

Study Design

Type

Observational (n=144)

Structured PICO

Does antihypertensive treatment improve heart rate variability and hemodynamic profiles in patients with primary arterial hypertension?

P
Population
144 patients with uncomplicated arterial hypertension followed for 12 months to assess the effects of antihypertensive treatment on heart rate variability and hemodynamic profiles.
E
Exposure
Antihypertensive treatment
O
Outcome
Correlation between heart rate variability (HRV) parameters and hemodynamic profile assessed via echocardiography and impedance cardiographysurrogate

Effective antihypertensive treatment is associated with improvements in both autonomic nervous system balance and hemodynamic profiles in patients with uncomplicated arterial hypertension.

Cite This Study

Maciorowska et al. (2022) conducted an observational in Primary arterial hypertension (n=144). Antihypertensive treatment was evaluated on Correlation between heart rate variability parameters and hemodynamic profile. Heart rate variability parameters of increased autonomic nervous system activity correlated with improved left ventricle function and lower left ventricular afterload.

synapsesocial.com/papers/6a9bd91d7c77d95ebc6bec81https://doi.org/10.3390/jcm11133767
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Value of Noninvasive Hemodynamics to Achieve Blood Pressure Control in Hypertensive Subjects2006 · 100 citations
  2. 2An Overview of Heart Rate Variability Metrics and Norms2017 · 7,281 citations
  3. 3Heart Rate Variability: Measurement and Clinical Utility2005 · 1,304 citations
  4. 4Non-invasive cardiovascular imaging for evaluating subclinical target organ damage in hypertensive patients2017 · 77 citations