Solvent‐Free Buchwald–Hartwig Reaction of Aryl and Heteroaryl Halides with Secondary Amines

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A highly efficient solvent‐free protocol for the Buchwald–Hartwig amination of (hetero)aryl halides by secondary amines was developed. The reaction is mediated by a Pd(OAc)2/RuPhos catalytic system in air. Various (hetero)aryl halides were coupled with diaryl, alkyl–aryl, and dialkylamines in good to excellent yields (51 examples, 50–99 % yield).