Key result
Primary pleural Ewing's sarcoma is an extremely rare and highly malignant tumor that was successfully treated with alternating VDC/IE chemotherapy and surgical resection, showing no recurrence at 6 months in the reported case.
Why the study?
Extraskeletal Ewing sarcoma accounts for less than 1% of all sarcomas and rarely arises in the pleura, prompting this report to improve understanding of its clinical and imaging characteristics.
Case Report (n=8)
Primary pleural Ewing's sarcoma is an extremely rare and highly malignant tumor that lacks specific clinical and imaging manifestations, requiring pathological and immunohistochemical analysis for definitive diagnosis.
Pleural EES in young adults warrants inclusion in thoracic mass differentials; extends the anatomic spectrum of this rare sarcoma.
Ewing sarcoma (ES) was first reported by Ewing in 1921. It is the second largest malignant bone tumor in children and adolescents, typically occurring in the bones of trunk or limbs . Extraskeletal Ewing sarcoma (EES) was first reported by Tefft et al. in 1969 and is extremely rare, accounting for less than 1% of all sarcomas. It can occur in any part of soft tissue, mostly in the trunk and lower limbs, and rarely in the pleura. We report a 22-year-old case of extraosseous Ewing sarcoma of pleural origin discovered and pathologically confirmed by physical examination. We report its CT manifestations and pathological results, and review the literature to summarize and analyze the clinical and imaging characteristics of extraosseous Ewing sarcoma, in order to improve our understanding of the disease.
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Yu et al. (2023) conducted a case report in Extraskeletal Ewing sarcoma of the pleura (n=8). Chemotherapy and surgical resection was evaluated on Tumor recurrence or metastasis. Primary pleural Ewing's sarcoma is an extremely rare and highly malignant tumor that was successfully treated with alternating VDC/IE chemotherapy and surgical resection, showing no recurrence at 6 months in the reported case.
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