Key result
A 14-year-old male with primary Ewing's sarcoma of the pleura died 1 year after diagnosis despite receiving chemo- and radiotherapy.
Why the study?
Primary extraskeletal Ewing sarcoma of the pleura is an uncommon condition that is challenging to diagnose, rarely reported, and can present with unusual clinical manifestations.
Case Report (n=1)
No
This report highlights a rare case of primary Ewing's sarcoma originating in the parietal pleura presenting with massive pleural effusion.
Rare pleural EES case in an adolescent warrants inclusion in effusion differentials; leaves open optimal management strategies.
Ewing's sarcoma was first reported by J.Ewing in 1921, which is generally originated from soft tissue of the trunk or limbs. Primary Extraskeletal Ewing sarcoma (EES) of pleura is an uncommon condition, which is challenging to diagnose, and rarely reported. Herein, we present a previously 14-year-old male patient with fever and dyspnea for 1 month presented to the department of respiratory medicine in Binzhou Medical University Hospital. Radiology revealed a soft mass with massive pleural effusion in the right side of pleural cavity. After admission, we performed the transthoracic catheter drainage for the patient, followed by thoracoscopy and biopsy. Histopathology revealed a small round cell malignant tumor, combined with immunohistochemistry assay and the Fluorescence in-situ hybridization (FISH) detection of EWSR1 gene arrangement, Ewing's sarcoma was finally diagnosed. Despite receiving chemo- and radiotherapy, the patient died 1 year later after diagnosis. This paper reports a rare case that originated in parietal pleura with massive pleural effusion of Ewing's sarcoma, which was not previously reported. This rare tumor and its unusual clinical manifestations prompt us to report the current case.
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Zou et al. (2021) conducted a case report in Primary Extraskeletal Ewing sarcoma (EES) of pleura (n=1). Chemo- and radiotherapy was evaluated on Mortality. A 14-year-old male with primary Ewing's sarcoma of the pleura died 1 year after diagnosis despite receiving chemo- and radiotherapy.
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