Key result
Ventricular premature complexes, ST-segment depression, and age independently predicted 5-year mortality among men with effort angina without prior myocardial infarction.
Why the study?
Does the presence of ventricular premature complexes during 1-hour ECG monitoring predict 5-year mortality in men with effort angina without prior myocardial infarction?
Cohort (n=2,155)
Does the presence of ventricular premature complexes during 1-hour ECG monitoring predict 5-year mortality in men with effort angina without prior myocardial infarction?
Ventricular premature complexes detected during a 1-hour ECG monitoring independently predict 5-year mortality in men with effort angina and no prior myocardial infarction.
Answers are grounded in this paper and cite their sources.
VPCs on brief ECG monitoring may aid risk stratification in effort angina without prior MI; leaves open whether this guides therapy in contemporary cohorts.
We studied the prognostic role of ventricular premature complexes occurring during 1 hour of electrocardiographic monitoring of 416 men with effort angina who had never had myocardial infarction, and compared mortality over 5 years with that of 1739 men with infarction before first observation. Multivariate analyses of survival identified the presence of ventricular premature complexes in 1 hour of monitoring, the presence of ST-segment depression on the standard ECG, and age as the variables making the most important independent contributions to risk of death (all causes and sudden coronary deaths) among the men with angina. The relatively lower age-adjusted 5-year mortality among men with angina compared with those who had a prior myocardial infarction reflects the lower prevalence in the former group of indicators of myocardial dysfunction, such as ventricular ectopic activity and ST-segment depression.
No takes yet. Share an insight, caveat, or question.
Ruberman et al. (1980) conducted a cohort in Effort angina and prior myocardial infarction (n=2,155). Ventricular premature complexes vs. Absence of ventricular premature complexes / Prior myocardial infarction was evaluated on Risk of death (all causes and sudden coronary deaths). Ventricular premature complexes, ST-segment depression, and age independently predicted 5-year mortality among men with effort angina without prior myocardial infarction.
Synapse has enriched 10 related papers. Consider them for comparative context: