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August 24, 2017The Journal of Immunology

Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs

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Authors

MAMartin AchleitnerTechnische Universität DresdenMKMartin KleefischAHAlexander HennigUniversity of Stuttgart

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Achleitner et al. (2017) studied this question.

synapsesocial.com/papers/6a9bfdc3dc2439d986623d91https://doi.org/10.4049/jimmunol.1700714
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Also Consider

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  1. 1Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity2014 · 234 citations
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  3. 3Aicardi–Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion2017 · 85 citations
  4. 4Defective removal of ribonucleotides from DNA promotes systemic autoimmunity2014 · 227 citations