Key result
Balloon atrial septostomy using a new low-profile catheter safely increased aortic saturation from 72% to 87% (P<0.001) and defect diameter from 2.7 mm to 8 mm (P<0.001) in neonates and infants.
Why the study?
Does balloon atrial septostomy using a new low-profile balloon catheter improve hemodynamics and defect size in neonates and infants with congenital heart disease?
Observational (n=17)
Does balloon atrial septostomy using a new low-profile balloon catheter improve hemodynamics and defect size in neonates and infants with congenital heart disease?
p-value: p=<.001
A new low-profile septostomy balloon catheter is safe and effective for creating a large atrial defect and improving hemodynamics in small neonates and infants with congenital heart disease.
No takes yet. Share an insight, caveat, or question.
May offer a feasible option for palliation in small neonates; hypothesis-generating pending larger comparative studies.
Hijazi et al. (1997) conducted an observational in Congenital heart disease requiring palliation (n=17). Low-profile end-hole septostomy balloon catheter vs. Pre-procedure baseline was evaluated on Aortic saturation, gradient across the atrial septum, and diameter of the defect (p=<.001). Balloon atrial septostomy using a new low-profile catheter safely increased aortic saturation from 72% to 87% (P<0.001) and defect diameter from 2.7 mm to 8 mm (P<0.001) in neonates and infants.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: