Key result
Measured posterior annuloplasty significantly reduced mitral regurgitation grade from 3.8 to 0.1 (P<0.0001) with 100% freedom from MPA-related reoperations over a mean 57.4 months.
Why the study?
Does measured posterior annuloplasty (MPA) improve mitral regurgitation and functional status in patients with non-ischemic mitral regurgitation?
Cohort (n=103)
No
Does measured posterior annuloplasty (MPA) improve mitral regurgitation and functional status in patients with non-ischemic mitral regurgitation?
Measured posterior annuloplasty is a durable technique for repairing non-ischemic mitral regurgitation, significantly reducing MR grade and improving NYHA functional class with a 100% freedom from MPA-related reoperations.
Answers are grounded in this paper and cite their sources.
Supports durability of MPA in non-ischemic MR; leaves open need for randomized trials.
UNLABELLED: The aim of this report is to evaluate short- and long-term outcomes of annuloplasty method of our choice: measured posterior annuloplasty (MPA). MPA is a piece of a Duran ring cut to the length of free-edge of anterior mitral leaflet (AML) and anchored with multiple pledgeted U-sutures from trigone to trigone into the posterior annulus. MATERIAL AND METHODS: From 1988 to 2000, 103 consecutive patients with non-ischemic mitral regurgitation were scheduled preoperatively to be repaired by MPA. RESULTS: Preoperative mitral valve regurgitation (MR) grade was 3.8+/-0.5 and decreased to 0.1+/-0.3 (P<0.0001) after repair. One patient was converted to insertion of mechanical prosthesis after grade 3 MR persisted after septal myectomy and MPA. Three patients needed instant revision of the repair one due to SAM and two due to stenosis. No patient had a stenosis or unacceptable (>1) MR after the procedure. There was one operative death (1.0%) and 3 hospital/30-day deaths (2.9%). Sixteen patients (16.3%) expired during the follow-up to 91 months (mean 57.4+/-19.5, median 60 months) none due to failure of MPA. There were no reoperations due to failure of MPA. Three patients had a reoperation, one for dehiscence of reconstruction after P2 resection and two patients due to progression of anterior leaflet degeneration and calcification with 4+ MR. New York Heart Association (NYHA) functional classification decreased from 2.3+/-0.8 to 1.4+/-0.6 (P<0.0001) and only one patient had an increase from II to III. Eighty-eight patients (96.7%) were in NYHA class I-II. Ten patients had an increase of MR from 0 to trace or 1 and one from 0 to 2. Two patients were diagnosed with mild stenosis without need of reoperation. CONCLUSIONS: MPA is a durable and stable alternative for repair of non-ischemic mitral regurgitation of different etiologies. The technique gives an objective measure of the length of the band and no patient is left with a significant MR or mitral valve stenosis (MS). First-time success rate is very high and instant repairs few and minor. Freedom of MPA related reoperations is 100%.
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Jyrala et al. (2009) conducted a cohort in non-ischemic mitral regurgitation (n=103). Measured posterior annuloplasty (MPA) vs. Preoperative baseline was evaluated on Mitral valve regurgitation (MR) grade (p=<0.0001). Measured posterior annuloplasty significantly reduced mitral regurgitation grade from 3.8 to 0.1 (P<0.0001) with 100% freedom from MPA-related reoperations over a mean 57.4 months.
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