Why the study?
Does the addition of CRT to optimal medical therapy and ICD reduce mortality and HF hospitalization in patients with mild to moderate HF symptoms, LV dysfunction (EF ≤ 30%) and wide QRS duration?
Population
1798 patients with mild to moderate heart failure symptoms requiring an implantable…
Comparison
Cardiac resynchronization therapy added to… vs Implantable cardioverter-defibrillator and…
Design
RCT, 1:1 ratio, double-blinded
Follow-up
mean ~36 months
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This abstract describes the design and baseline characteristics of a randomized trial evaluating the addition of CRT to ICD in mild-to-moderate heart failure, with results pending.
RCT (n=1,798)
Double-blind
1:1 ratio
Yes
Does the addition of CRT to optimal medical therapy and ICD reduce mortality and HF hospitalization in patients with mild to moderate HF symptoms, LV dysfunction (EF ≤ 30%) and wide QRS duration?
This abstract describes the design and baseline characteristics of a randomized trial evaluating the addition of CRT to ICD in mild-to-moderate heart failure, with results pending.
A 2010 study conducted an RCT in Mild to moderate heart failure (n=1,798). ICD with CRT vs. ICD (control) was evaluated on Composite of all cause mortality and adjudicated HF hospitalization. This trial enrolled 1,798 patients to evaluate whether adding cardiac resynchronization therapy to an ICD reduces mortality and heart failure hospitalization, with final results pending.
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