Key result
Pre-existing heart disease in pregnant women was associated with a higher rate of neonatal complications compared to matched healthy controls (18% vs 7%).
Why the study?
Can clinical predictors identify pregnant women with pre-existing heart disease at high risk for maternal and neonatal complications?
Population
Pregnant women with pre-existing heart disease
Comparison
Clinical risk prediction rule based on maternal… vs Matched pregnancies with no underlying heart…
Design
Review
Follow-up
completed gestations
Authors
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Supports closer neonatal monitoring in maternal heart disease pregnancies; leaves open prospective validation of clinical predictors.
Observational (n=1,447)
Yes
Can clinical predictors identify pregnant women with pre-existing heart disease at high risk for maternal and neonatal complications?
Absolute Event Rate: 18% vs 7%
Maternal and neonatal morbidity are significantly increased in pregnant women with pre-existing heart disease, and risk can be accurately predicted using specific clinical factors to guide management.
Sermer et al. (2003) conducted an observational in Pregnancy complicated by heart disease (n=1,447). Pre-existing heart disease vs. No underlying heart disease was evaluated on Neonatal complications. Pre-existing heart disease in pregnant women was associated with a higher rate of neonatal complications compared to matched healthy controls (18% vs 7%).
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