Early repolarization on ECG (early repolarization pattern and syndrome)

PurposeTo study the early repolarization pattern (ERP) in patient with nonischemic cardiomyopathies (acute myocarditis and arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C)). Materials and methods: We analyzed 2 groups of patients: The 1st group — 29 patients with acute myocarditis (21 male, age 48,7±13,5); the 2nd — 51 patients with confirmed diagnose of ARVD/C (27 male, age 33±7). We used the criteria by Macfarlane P.W. et al., 2015 to identify ERP. Also we analyzed the results of endomiocardial biopsy (EMB). Results:In the 1st group ERP was detected in 13,8% (4) patients), in the 2nd ERP was detected in 17,6% (9) patients. There was no significant difference between frequency of ERP in these groups (p>0.05In the 1st group in all patients was detected inflammation by EMB, myocardial fibrosis was found in 25% (1) patients. In the 2nd group in 22,2% (2) patients with ERP there were no structural abnormalities detected by EMB, and other 78% patients had residual myocytes. Conclusions.On the example of myocarditis and ARVD/C we demonstrated that the ERP was not studied for all diseases that have a pathogenetic basis for its occurrence. Further prospective studies are necessary to evaluate the relationship with the arrhythmias, including malignant ones.