Key result
Early repolarization pattern linked to ~192% greater 30-day VT/VF risk in acute anterior STEMI.
Why the study?
The association between early repolarization pattern and ventricular arrhythmias in patients with STEMI remains uncertain.
Does the early repolarization pattern predict the risk of sustained VT/VF in patients with acute anterior STEMI?
Population
1,460 consecutive patients with acute anterior STEMI
Comparison
ERP-positive group vs ERP-negative group
Design
Propensity score-adjusted observational cohort study
Follow-up
30 days
Authors
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ERP presence was associated with higher early VT/VF risk in anterior STEMI; leaves open its utility for acute risk stratification.
Observational (n=1,460)
Yes
Does the early repolarization pattern predict the risk of sustained VT/VF in patients with acute anterior STEMI?
Hazard Ratio: 2.915 (95% CI 1.52–5.588)
Absolute Event Rate: 10.4% vs 4.7%
p-value: p=0.001
The presence of an early repolarization pattern is an independent predictor of sustained ventricular tachycardia or fibrillation within 30 days in patients with acute anterior STEMI.
Chen et al. (2017) conducted an observational in Acute anterior ST-segment elevation myocardial infarction (STEMI) (n=1,460). Early repolarization pattern (ERP) vs. No early repolarization pattern was evaluated on Sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) within 30 days (HR 2.915, 95% CI 1.520-5.588, p=0.001). The presence of an early repolarization pattern was associated with a significantly increased 30-day risk of sustained ventricular tachycardia or fibrillation (HR 2.915) in patients with acute anterior STEMI.
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