Key result
In situ hybridization demonstrated that the human cardiac myosin heavy chain genes (MYH6 and MYH7) are located within the q12 band of chromosome 14.
Population
Human chromosomes (in situ hybridization model)
Design
Preclinical
Authors
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No immediate clinical impact; extends cytogenetic mapping for cardiomyopathy gene studies.
The study precisely localized the human cardiac beta-myosin heavy chain gene (MYH7) to chromosome 14q12.
Kemp et al. (2008) studied this question. In situ hybridization was evaluated on Chromosomal localization of human cardiac MHC genes. In situ hybridization demonstrated that the human cardiac myosin heavy chain genes (MYH6 and MYH7) are located within the q12 band of chromosome 14.
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