Key result
Primary percutaneous coronary intervention in acute myocardial infarction patients aged ≥75 years showed comparable one-year major adverse cardiac events to those <75 years.
Why the study?
Does primary PCI for acute myocardial infarction in patients older than 75 years yield comparable clinical outcomes to younger patients?
Cohort (n=223)
No
Does primary PCI for acute myocardial infarction in patients older than 75 years yield comparable clinical outcomes to younger patients?
Answers are grounded in this paper and cite their sources.
Primary PCI in AMI patients older than 75 years can be performed with procedural success rates and long-term clinical outcomes comparable to those of younger patients.
Background and Objectives:Primary percutaneous coronary intervention (PCI) has been found to be superior, in terms of hospital mortality and long-term follow-up, compared with thrombolytic therapy for acute myocardial infarction (AMI). However, the clinical benefits of primary PCI have not been precisely evaluated in elderly patients. Subjects and Methods:Two hundred and twenty three patients (Group I: n=66, age≥75 years, Group II: n=157, age<75 years), who underwent primary PCI for AMI at Chonnam National University Hospital, between 2000 and 2002, were analyzed according to their clinical, angiographic characteristics, inhospital and one-year survival. Results:Group I had a higher percentage of women (45.5% vs. 19.1%, p= 0.00), multi-vessel disease (42% vs. 28%, p=0.031), right coronary artery disease (52% vs. 33%, p=0.021), and more frequent histories of diabetes mellitus (35% vs. 22%, p=0.039) and less smoking (38% vs. 60%, p= 0.003) than Group II. Successful reperfusion by PCI was achieved in 97 and 96 %, respectively (p=NS). The rates of in-hospital mortality were similar in both groups (12.1% vs. 8.2%, p=NS). There were no significant differences in the major adverse cardiac events between the two groups during the one-year clinical follow-up (31.4 % vs. 36.9 %, p=NS). Conclusion:Primary PCI in AMI patients older than 75 years can be performed with comparable procedural success rates and long-term clinical outcomes to those of younger patients. (Korean Circulation J 2005;35:613-619)
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Lim et al. (2005) conducted a cohort in Acute Myocardial Infarction (n=223). Age ≥75 years vs. Age <75 years was evaluated on Major adverse cardiac events (p=NS). Primary percutaneous coronary intervention in acute myocardial infarction patients aged ≥75 years showed comparable one-year major adverse cardiac events to those <75 years.
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