Key result
Primary PCI yields comparable STEMI mortality across ages, with CKD linked to ~11-fold higher risk.
Why the study?
Data regarding the safety and efficacy of primary PCI in elderly patients are scarce, and it was unclear whether the advantages of primary PCI diminish with advanced age.
Does primary percutaneous coronary intervention (P-PCI) result in comparable in-hospital and 30-day all-cause mortality in elderly patients (≥75 years) compared to younger patients (65-74 years) with acute STEMI?
Population
1111 elderly patients undergoing P-PCI for acute STEMI
Comparison
Ages 75-84 vs age >=85 vs ages 65-74
Design
Retrospective study
Follow-up
30-day
Authors
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May support P-PCI consideration in elderly STEMI; leaves open randomized confirmation of mortality equivalence.
Cohort (n=1,111)
Does primary percutaneous coronary intervention (P-PCI) result in comparable in-hospital and 30-day all-cause mortality in elderly patients (≥75 years) compared to younger patients (65-74 years) with acute STEMI?
Primary PCI for acute STEMI in elderly patients (≥75 years) yields comparable in-hospital and 30-day mortality outcomes to younger patients (65-74 years), supporting its use in this population.
Seif et al. (2022) conducted a cohort in acute STEMI (n=1,111). Primary percutaneous coronary intervention (P-PCI) vs. Patients aged 65-74 years was evaluated on in-hospital and 30-day all-cause mortality. Primary percutaneous coronary intervention for STEMI in elderly patients showed comparable mortality to younger patients, with CKD predicting in-hospital mortality (OR 11.024; 95% CI 2.104-57.756).