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Case report demonstrates secretory carcinoma of the parotid gland in a 22-year-old man, highlighting the clinical presentation of tumors driven by ETV6-NTRK3 fusion.
Mammary analog secretory carcinoma (MASC) is a newly described carcinoma with a molecular hallmark of ETV6-NTRK3 fusion that promotes oncogenesis. While MASC histopathology was well-studied in the literature, clinical behavior remains unstudied. We present a 22-year-old man with painless parotid mass, which was diagnosed as salivary gland cancer, MASC subtype.
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Alkaabba et al. (2022) studied this question.
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