Key result
A 45-year-old male with acute myocardial infarction and a history of cocaine abuse developed fatal diffuse pulmonary hemorrhage after receiving streptokinase.
Case Report (n=1)
No
Pulmonary hemorrhage is a rare but life-threatening complication of fibrinolytic therapy for acute myocardial infarction, which may be predisposed by cocaine and tobacco abuse.
May warrant caution with streptokinase in cocaine-associated AMI; hypothesis-generating for predisposition to pulmonary hemorrhage.
We report a 45-year-old man with antroseptal myocardial infarction who developed bilateral basal alveolar infiltrates after initiating the fibrinolytic therapy. Although thrombolytic therapy with streptokinase is generally used in the course of acute myocardial infarction and has diminished morbidity and mortality, pulmonary hemorrhage is an uncommon, but a potentially life-threatening complication that should be regarded as one of the differential diagnoses of pulmonary infiltrates or dropping hemoglobin with no apparent bleeding site.
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Khaheshi et al. (2014) conducted a case report in Acute myocardial infarction (n=1). Streptokinase was evaluated on Diffuse pulmonary hemorrhage. A 45-year-old male with acute myocardial infarction and a history of cocaine abuse developed fatal diffuse pulmonary hemorrhage after receiving streptokinase.
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