Key result
Male patients with osteoporotic hip fractures had a significantly higher incidence of secondary osteoporosis compared to female patients (50% vs 13%, p<0.001).
Why the study?
Osteoporosis and osteoporotic fractures carry increased morbidity and mortality, but osteoporosis in men remains underdiagnosed and undertreated.
Observational (n=140)
No
Absolute Event Rate: 50% vs 13%
p-value: p=<0.001
Elderly men with osteoporotic hip fractures have a significantly higher prevalence of secondary osteoporosis compared to women, highlighting the need for targeted screening in this population.
May support targeted secondary osteoporosis evaluation in men with hip fractures; hypothesis-generating and requires prospective confirmation.
BackgroundOsteoporosis and osteoporotic fracture pose a major public health problem in our aging population and carry an increased morbidity and mortality. While overall diagnosis and treatment for osteoporosis have improved, osteoporosis in men remain underdiagnosed and undertreated.AimWe aim to describe the difference in clinical characteristics between elderly men and women with osteoporotic hip fractures in Sarawak General Hospital.MethodsAll patients diagnosed with osteoporotic hip fracture admitted from June 2019-March 2021 were recruited and demographic data and clinical features were obtained.ResultsThere were 140 patients with osteoporotic hip fracture, and 40 were men (28.6%). The mean age for males were 74.1 ± 9.5 years, while the mean age for females were 77.4 ± 9.1 years (p=0.06). There were 20 men with secondary osteoporosis (50%), while 13 women (13%) had secondary osteoporosis (p<0.001). The causes of secondary osteoporosis among the men were hypogonadism, COPD, GIOP, renal disease, ADT, thyroid disorder, prostate cancer, and previous gastrectomy. There were two deaths among the men and four deaths among the women during the inpatient and 3 months follow up period. There was no statistical significance between the mortality rates between male patients (5%) and female patients (4%) (p=0.55). ConclusionThere were more females with osteoporotic hip fractures, and there were significantly more males with secondary osteoporotic hip fractures.Trial registration: This study (Male osteoporotic hip fracture in Sarawak General Hospital) was registered with the Malaysian National Medical Research Register (NMRR). Trial registration number: NMRR-19-323-46068 IIR
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Wan et al. (2021) conducted an observational in Osteoporotic hip fracture (n=140). Male gender vs. Female gender was evaluated on Incidence of secondary osteoporosis (p=<0.001). Male patients with osteoporotic hip fractures had a significantly higher incidence of secondary osteoporosis compared to female patients (50% vs 13%, p<0.001).
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