Key result
Male hip fracture patients are linked to a ~285% higher prevalence of secondary osteoporosis than females.
Why the study?
Osteoporotic hip fractures carry increased morbidity and mortality with differences between sexes, but osteoporosis in men remains underdiagnosed and undertreated.
Are there gender differences in clinical characteristics and outcomes among elderly patients with osteoporotic hip fractures?
Observational (n=140)
No
Are there gender differences in clinical characteristics and outcomes among elderly patients with osteoporotic hip fractures?
Absolute Event Rate: 50% vs 13%
p-value: p=<0.001
Elderly men with osteoporotic hip fractures are significantly more likely to have secondary causes of osteoporosis compared to women, highlighting the need for targeted evaluation in this population.
May support targeted secondary osteoporosis evaluation in elderly men with hip fractures; leaves open effects on outcomes and management.
BackgroundOsteoporosis and osteoporotic fracture pose a major public health problem in our aging population. Osteoporotic hip fractures carry an increased morbidity and mortality, with some difference seen between men and women. While overall diagnosis and treatment for osteoporosis have improved, osteoporosis in men remain underdiagnosed and undertreated.AimWe aim to describe the difference in clinical characteristics between elderly men and women with osteoporotic hip fractures in Sarawak General Hospital.MethodsAll patients diagnosed with osteoporotic hip fracture admitted to Sarawak General Hospital from June 2019-March 2021 were recruited and demographic data and clinical features were obtained.ResultsThere were 140 patients with osteoporotic hip fracture, and 40 were men (28.6%). The mean age for males were 74.1 ± 9.5 years, while the mean age for females were 77.4 ± 9.1 years (p=0.06). The types of fracture consisted of neck of femur=78, intertrochanteric=61, and subtrochanteric=1. There were 20 men with secondary osteoporosis (50%), while 13 women (13%) had secondary osteoporosis (p<0.001). The causes of secondary osteoporosis among the men were hypogonadism, COPD, GIOP, renal disease, ADT, thyroid disorder, prostate cancer, and previous gastrectomy. There were two deaths among the men and four deaths among the women during the inpatient and 3 months follow up period. There was no statistical significance between the mortality rates between male patients (5%) and female patients (4%) (p=0.55). ConclusionThere were more females with osteoporotic hip fractures, and there were significantly more males with secondary osteoporotic hip fractures.Trial registration: This study (Male osteoporotic hip fracture in Sarawak General Hospital) was registered with the Malaysian National Medical Research Register (NMRR). Trial registration number: NMRR-19-323-46068 IIR
No takes yet. Share an insight, caveat, or question.
Wan et al. (2021) conducted an observational in Osteoporotic hip fracture (n=140). Male gender vs. Female gender was evaluated on Secondary osteoporosis (p=<0.001). Male patients with osteoporotic hip fractures had a significantly higher prevalence of secondary osteoporosis compared to female patients (50% vs 13%, p<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: