Key result
Intravenous streptokinase effectively achieved tricuspid prosthetic valve thrombolysis in a 26-year-old female with Ebstein's anomaly.
Why the study?
Prosthetic heart valve thrombosis remains a dreadful complication associated with high mortality, and medical thrombolysis represents an alternative therapy choice to conventional surgical treatment.
Does intravenous streptokinase effectively treat tricuspid prosthetic valve thrombosis in a patient with Ebstein's anomaly?
Case Report (n=1)
Does intravenous streptokinase effectively treat tricuspid prosthetic valve thrombosis in a patient with Ebstein's anomaly?
Intravenous streptokinase may be an adequate therapeutic option for thrombolysis of tricuspid prosthetic valve thrombosis in young patients.
May support streptokinase in rare tricuspid prosthetic thrombosis with Ebstein's anomaly; hypothesis-generating and requires validation.
Despite improvements in the design of mechanical prosthetic heart valves and regular use of anticoagulation, prosthetic heart valve thrombosis remain the most dreadful complication associated with high mortality. Surgical thrombectomy or valvereplacement is used as a conventional therapy. Medical thrombolysis, on the other hand, is a therapy choice. Present case is of a 26-year old female with Ebstein's irregularity who effectively endured tricuspid prosthetic valve thrombolysis usingintravenous Streptokinase (SK). The outcome of our patient supports that SK can be an adequate therapeutic option for thrombolysis of tricuspid Prosthetic Valve Thrombosis (PVT) in children and adolescents.
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Azizullah et al. (2023) conducted a case report in Prosthetic Tricuspid Valve Thrombosis (n=1). Intravenous Streptokinase was evaluated on Thrombolysis. Intravenous streptokinase effectively achieved tricuspid prosthetic valve thrombolysis in a 26-year-old female with Ebstein's anomaly.
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