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May 8, 2018Mayo Clinic Proceedings Innovations Quality & OutcomesOpen Access

Cardiorespiratory Fitness Is Inversely Associated With Clustering of Metabolic Syndrome Risk Factors: The Ball State Adult Fitness Program Longitudinal Lifestyle Study

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Key result

Higher cardiorespiratory fitness was inversely associated with metabolic syndrome, with the highest fitness quartile having lower odds than the lowest (OR 0.10; 95% CI 0.07-0.14; P<0.001).

Why the study?

Is higher cardiorespiratory fitness associated with a lower prevalence of metabolic syndrome in adults?

Population

3636 adults who completed cardiorespiratory fitness and metabolic risk factor assessment.

Comparison

Higher cardiorespiratory fitness defined as… vs Lowest quartile of cardiorespiratory fitness.

Design

Cohort

Authors

EKElizabeth P. KelleyQueen's UniversityMIMary T. ImbodenProvidence St. Vincent Medical CenterMHMatthew P. HarberBall State University

Discussion

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Implication

May support fitness assessment in metabolic risk stratification; leaves open whether improving fitness reduces incidence.

Study Design

Type

Cohort (n=3,636)

Structured PICO

Is higher cardiorespiratory fitness associated with a lower prevalence of metabolic syndrome in adults?

P
Population
3,636 adults (44.8% female, mean age 44.7 years) who completed cardiorespiratory fitness and metabolic risk factor assessments.
E
Exposure
Higher cardiorespiratory fitness (CRF) defined as measured VO2max from a cardiopulmonary exercise test on a treadmill.
C
Comparator
Lowest quartile of cardiorespiratory fitness.
O
Outcome
Presence of metabolic syndrome (≥3 metabolic markers).surrogate

Main Result

Odds Ratio: 0.1 (95% CI 0.07–0.14)

p-value: p=<.001

Higher objectively measured cardiorespiratory fitness is strongly and inversely associated with the prevalence of metabolic syndrome in both men and women.

Cite This Study

Kelley et al. (2018) conducted a cohort in Metabolic syndrome (n=3,636). Cardiorespiratory fitness (VO2max) vs. Lowest fitness quartile was evaluated on Metabolic syndrome (≥3 risk factors) (OR 0.10, 95% CI 0.07-0.14, p=<.001). Higher cardiorespiratory fitness was inversely associated with metabolic syndrome, with the highest fitness quartile having lower odds than the lowest (OR 0.10; 95% CI 0.07-0.14; P<0.001).

synapsesocial.com/papers/6a9c5190a84bc2d98a241c2ahttps://doi.org/10.1016/j.mayocpiqo.2018.03.001
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Also Consider

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