Key result
Same-volume double-tap post-dilatation during TAVI linked to ~11% greater mid-portion THV expansion.
Why the study?
Transcatheter heart valve underexpansion is linked to haemodynamic deterioration, and double inflation using the delivery balloon with unchanged volume may improve expansion while minimizing complication risks.
Does same-volume double-tap post-dilatation improve THV expansion and deformation in patients undergoing TAVI for severe native aortic stenosis?
Observational (n=113)
Does same-volume double-tap post-dilatation improve THV expansion and deformation in patients undergoing TAVI for severe native aortic stenosis?
Routine double-tap post-dilatation of balloon-expandable valves during TAVI significantly improves transcatheter heart valve expansion and frame deformation.
Double-tap may optimize S3UR expansion post-TAVI without added risk; hypothesis-generating and requires randomized confirmation before practice change.
Background Transcatheter heart valve (THV) underexpansion is associated with haemodynamic valve deterioration. Double inflation of balloon-expandable valves using the delivery balloon with unchanged volume (double-tap) may improve THV expansion, while minimizing the risk of complications. Aims To evaluate the efficacy of double-tap after transcatheter aortic valve implantation (TAVI) with SAPIEN-3 Ultra RESILIA (S3UR) valves. Methods This observational study included consecutive patients who underwent TAVI for severe native aortic stenosis and had same-volume double-tap, from November 2024 to September 2025. THV expansion and deformation were assessed fluoroscopically before and after double-tap after appropriate calibration. Thirty-day clinical outcomes were reported. Results Of 113 patients who underwent TAVI with same-volume double-tap (mean age: 79.3 ± 7.3 years, 26.5% female, 13.3% bicuspid anatomy), the median THV expansion before double-tap, at the inflow, mid-portion, and outflow was 88.6% (IQR: 86.4–90.4%), 80.1% (IQR: 77.3–82.3%), and 90.1% (IQR: 88.4–90.9%) respectively, and after double-tap increased to 96.4% (IQR: 94.6–98.4%), 90.8% (IQR: 88.6–92.9%), and 97.6% (IQR: 96.3–99.0%) (all P < .001). The largest increase in expansion following double-tap occurred in the THV mid-portion (median: 10.6% [IQR: 9.8–11.6%]). Multivariable predictors of the extent of minimum expansion improvement following double-tap were bicuspid anatomy (P = .005) and aortic valve calcium volume of >385 mm3 (median) (P = .046). The median THV deformation index decreased from 1.05 (IQR: 1.04–1.07) to 1.03 (IQR: 1.02–1.04) after double-tap (P < .001). Thirty-day mortality rate was 0.9%. Conclusion Routine double-tap post-dilatation of balloon-expandable valves improves THV expansion and frame deformation, without any clear safety signal. Bicuspid anatomy and aortic valve calcium burden predicted the extent of expansion improvement.
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Maznyczka et al. (2026) conducted an observational in Severe native aortic stenosis (n=113). Same-volume double-tap post-dilatation vs. Before double-tap was evaluated on THV expansion at the mid-portion (p=<.001). Same-volume double-tap post-dilatation during TAVI significantly increased median THV expansion at the mid-portion from 80.1% to 90.8% (P<.001).
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