Key result
Balloon valvuloplasty showed no significant difference in freedom from reintervention compared to surgical valvotomy at a mean follow-up of 5.3 years (69% vs 70%, p = 1.0).
Why the study?
Choice of balloon valvuloplasty versus surgical aortic valvotomy for congenital aortic stenosis often depends on center bias, with limited contemporary comparative literature.
Does balloon aortic valvuloplasty compared to surgical aortic valvotomy improve freedom from reintervention in patients with congenital aortic stenosis?
Cohort (n=142)
Yes
Does balloon aortic valvuloplasty compared to surgical aortic valvotomy improve freedom from reintervention in patients with congenital aortic stenosis?
Absolute Event Rate: 69% vs 70%
p-value: p=1.0
Balloon aortic valvuloplasty and surgical aortic valvotomy demonstrate comparable medium-term freedom from reintervention in children with congenital aortic stenosis.
Supports individualized choice between approaches in congenital aortic stenosis; leaves open need for randomized trials.
BACKGROUND: Balloon valvuloplasty and surgical aortic valvotomy have been the treatment mainstays for congenital aortic stenosis in children. Choice of intervention often differs depending upon centre bias with limited relevant, comparative literature. OBJECTIVES: This study aims to provide an unbiased, contemporary matched comparison of these balloon and surgical approaches. METHODS: Retrospective analysis of patients with congenital aortic valve stenosis who underwent balloon valvuloplasty (Queensland Children's Hospital, Brisbane) or surgical valvotomy (Royal Children's Hospital, Melbourne) between 2005 and 2016. Patients were excluded if pre-intervention assessment indicated ineligibility to either group. Propensity score matching was performed based on age, weight, and valve morphology. RESULTS: Sixty-five balloon patients and seventy-seven surgical patients were included. Overall, the groups were well matched with 18 neonates/25 infants in the balloon group and 17 neonates/28 infants in the surgical group. Median age at balloon was 92 days (range 2 days - 18.8 years) compared to 167 days (range 0 days - 18.1 years) for surgery (rank-sum p = 0.08). Mean follow-up was 5.3 years. There was one late balloon death and two early surgical deaths due to left ventricular failure. There was no significant difference in freedom from reintervention at latest follow-up (69% in the balloon group and 70% in the surgical group, p = 1.0). CONCLUSIONS: Contemporary analysis of balloon aortic valvuloplasty and surgical aortic valvotomy shows no difference in overall reintervention rates in the medium term. Balloon valvuloplasty performs well across all age groups, achieving delay or avoidance of surgical intervention.
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A 2021 study conducted a cohort in Congenital aortic valve stenosis (n=142). Balloon valvuloplasty vs. Surgical valvotomy was evaluated on Freedom from reintervention at latest follow-up (p=1.0). Balloon valvuloplasty showed no significant difference in freedom from reintervention compared to surgical valvotomy at a mean follow-up of 5.3 years (69% vs 70%, p = 1.0).
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