Key result
Balloon aortic valvuloplasty and surgical valvotomy provided similar post-procedure mean gradients (25.8 vs 26.2 mmHg, p=0.87), though balloon valvuloplasty had more significant aortic insufficiency.
Why the study?
Balloon aortic valvuloplasty and open surgical valvotomy both treat neonatal aortic stenosis, but controversy remains regarding which method provides superior outcomes.
Does balloon aortic valvuloplasty improve outcomes compared to surgical valvotomy in neonates with aortic stenosis?
Comparison
Balloon aortic valvuloplasty vs surgical valvotomy via open commissurotomy
Design
Single-institution retrospective cohort study
Follow-up
5 years
Authors
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Both approaches show comparable short-term outcomes in this small cohort; leaves open optimal initial strategy for neonatal aortic stenosis.
Cohort (n=55)
No
Does balloon aortic valvuloplasty improve outcomes compared to surgical valvotomy in neonates with aortic stenosis?
Absolute Event Rate: 25.8% vs 26.2%
p-value: p=0.87
Balloon aortic valvuloplasty and surgical valvotomy offer similar short-term gradient reduction and re-intervention rates in neonates, but balloon valvuloplasty carries a higher risk of aortic insufficiency.
Zaban et al. (2020) conducted a cohort in Neonatal aortic stenosis (n=55). Balloon aortic valvuloplasty vs. Surgical valvotomy via an open commissurotomy was evaluated on Post-procedure mean gradient by transthoracic echocardiogram (p=0.87). Balloon aortic valvuloplasty and surgical valvotomy provided similar post-procedure mean gradients (25.8 vs 26.2 mmHg, p=0.87), though balloon valvuloplasty had more significant aortic insufficiency.
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