Key result
Atherosclerosis-like lesions in the aortic valve were present in 45 of 48 unselected adult necropsy subjects, with mean lesion area increasing significantly with age (p < 0.001).
Observational (n=48)
No
p-value: p=< 0.001
Atherosclerosis-like lesions in the aortic valve are highly prevalent across all adult age groups, suggesting that the pathophysiological process leading to aortic stenosis often begins in early adulthood.
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Aortic valve lesions may begin early in adulthood; leaves open whether early prevention modifies stenosis risk.
Johanna Kuusisto (2005) conducted an observational in Atherosclerosis-like lesions of the aortic valve (n=48). Age vs. Younger age was evaluated on Detection of the presence of atherosclerosis-like lesions and mineralisation in aortic valves, and morphometrical measurement of the size of lesions (p=< 0.001). Atherosclerosis-like lesions in the aortic valve were present in 45 of 48 unselected adult necropsy subjects, with mean lesion area increasing significantly with age (p < 0.001).
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