Key result
Levosimendan infusion in three pediatric patients with severe refractory heart failure improved ejection fraction (to 34-44%) and stroke volume (to 59-93 mL/m2).
Why the study?
Does levosimendan improve hemodynamics and echocardiographic parameters in pediatric patients with severe acute congestive heart failure refractory to standard inotropes?
Population
3 pediatric patients with severe acute deterioration of previously diagnosed chronic heart failure…
Design
Case_series
Authors
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May support levosimendan rescue use in refractory pediatric HF; leaves open need for controlled trials.
Case Report (n=3)
Does levosimendan improve hemodynamics and echocardiographic parameters in pediatric patients with severe acute congestive heart failure refractory to standard inotropes?
Levosimendan infusion may provide significant clinical and hemodynamic improvement as a rescue therapy in pediatric patients with severe heart failure refractory to standard inotropes.
Prijić et al. (2011) conducted a case report in severe acute congestive heart failure (n=3). Levosimendan vs. standard intravenous inotropic agents was evaluated on clinical and echocardiography improvement. Levosimendan infusion in three pediatric patients with severe refractory heart failure improved ejection fraction (to 34-44%) and stroke volume (to 59-93 mL/m2).
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