Key result
Peripheral fat mass is hypothesized to influence the obesity paradox in heart failure, requiring further assessment of BMI as a potential confounder of cardiovascular risk.
Highlights the need to investigate whether BMI confounds the relationship between cardiovascular risk and peripheral adiposity in heart failure.
and (2) whether the previously described protective effects of peripheral fat mass has implications for the reported obesity paradox.It would be useful to assess whether BMI is a confounder of the association between cardiovascular risk and hip circumference, 5 if this latter anthropometric measure of peripheral adiposity was available for supplementary analysis.
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Kalantar‐Zadeh et al. (2005) studied this question. Peripheral fat mass is hypothesized to influence the obesity paradox in heart failure, requiring further assessment of BMI as a potential confounder of cardiovascular risk.
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