Key result
Moderate estimated cardiorespiratory fitness was associated with an 18% lower odds of depression (OR 0.82) compared to low cardiorespiratory fitness in adults.
Why the study?
The relationship between cardiorespiratory fitness and depression in adults remained to be assessed.
Does higher estimated cardiorespiratory fitness reduce the odds of depression in adults?
Cross-Sectional (n=52,611)
Yes
Does higher estimated cardiorespiratory fitness reduce the odds of depression in adults?
Higher estimated cardiorespiratory fitness is associated with significantly lower odds of depressive symptoms in adults.
Moderate CRF linked to lower depression odds warrants no practice change; leaves open causal effects of fitness interventions.
OBJECTIVE: This study assessed the relationship between cardiorespiratory fitness (CRF) and depression in adults. METHODS: A total of 52,611 individuals aged between 18-59 years old were evaluated for symptoms of depression and CRF. The presence of depressive symptoms was self-report through the Patient Health Questionnaire (PHQ-9), and the CRF was predicted from a non-exercise equation. The association between CRF and the presence of depression was determined by crude and multivariable-adjusted logistic regressions. RESULTS: The associations were identified between symptoms of depression and CRF in both unadjusted and adjusted models. After adjusting for age categories, sex, body mass index categories, educational level, marital status, smoking, and alcohol use, the individuals with moderate CRF had 18% lower odds of depression (OR: 0.82, CI 95%: 0.71 - 0.95) compared to individuals with low CRF. CONCLUSION: Depressive symptoms are inversely related to CRF levels in adults.
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Lattari et al. (2021) conducted a cross-sectional in Depression (n=52,611). Moderate estimated cardiorespiratory fitness (CRF) vs. Low estimated cardiorespiratory fitness (CRF) was evaluated on Presence of depressive symptoms (PHQ-9 ≥ 5) (OR 0.82, 95% CI 0.71-0.95, p=0.01). Moderate estimated cardiorespiratory fitness was associated with an 18% lower odds of depression (OR 0.82) compared to low cardiorespiratory fitness in adults.
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