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October 1, 1986Annals of SurgeryOpen Access

The First Open Heart Corrections of Tetralogy of Fallot

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Key result

Open heart correction of Tetralogy of Fallot resulted in an actuarial survival of 77% and freedom from reoperation of 91% at 30 years.

Why the study?

Does open heart correction of Tetralogy of Fallot improve long-term survival and functional outcomes in patients with Tetralogy of Fallot?

Population

106 patients who underwent open repairs of Tetralogy of Fallot at the University of Minnesota between 1954…

Design

Cohort

Follow-up

26-31 years (mean: 23.7 years)

Authors

CLC. Walton LilleheiBoston Children's HospitalRVRichard L. VarcoUniversity of MinnesotaHWHerbert E. WardenWest Virginia University

Discussion

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Implication

Supports durable 30-year outcomes after early TOF repair; extends observational data but leaves contemporary applicability open.

Study Design

Type

Cohort (n=106)

Multicenter

No

Structured PICO

Does open heart correction of Tetralogy of Fallot improve long-term survival and functional outcomes in patients with Tetralogy of Fallot?

P
Population
106 patients aged 4 months to 45 years who underwent open repair for Tetralogy of Fallot and were discharged, followed for a mean of 23.7 years.
E
Exposure
Open heart correction of Tetralogy of Fallot (using cross circulation in 6 patients and bubble oxygenator in 100 patients).
O
Outcome
Survival, morbidity, hemodynamics, educational/employment attainments, and relation of these to surgical technics.hard clinical

Long-term follow-up of the first open heart corrections of Tetralogy of Fallot demonstrates excellent 30-year survival (77%) and functional outcomes, highlighting the historical success of these pioneering surgeries.

Cite This Study

Lillehei et al. (1986) conducted a cohort in Tetralogy of Fallot (n=106). Open heart correction was evaluated on Actuarial survival at 30 years. Open heart correction of Tetralogy of Fallot resulted in an actuarial survival of 77% and freedom from reoperation of 91% at 30 years.

synapsesocial.com/papers/6a9c91ecffeecd27fa4a4b96https://doi.org/10.1097/00000658-198610000-00017
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