Key result
Among 9,747 children under 5 years of age with acute watery diarrhea and moderate to severe dehydration in Niger, 30.6% were positive for rotavirus, with G12P[8] emerging as the predominant strain.
Observational (n=9,747)
Yes
Rotavirus is a major cause of severe diarrhea in children in Niger, with G12P[8] emerging as the predominant strain, highlighting the need for continuous surveillance before vaccine introduction.
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Supports rotavirus surveillance in Niger pre-vaccine; leaves open G12P[8] impact on efficacy.
Page et al. (2014) conducted an observational in Acute watery diarrhea and moderate to severe dehydration (n=9,747). Rotavirus vs. Non-rotavirus diarrhea was evaluated on Rotavirus positivity (95% CI 29.7-31.5). Among 9,747 children under 5 years of age with acute watery diarrhea and moderate to severe dehydration in Niger, 30.6% were positive for rotavirus, with G12P[8] emerging as the predominant strain.
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