Key result
A large heart rate increase during mild mental stress before an exercise test predicted a higher long-term risk of sudden cardiac death (RR 2.09; 95% CI 1.13-3.86).
Why the study?
Does a large heart rate increase during mild mental stress predict sudden cardiac death in apparently healthy individuals?
Population
7,746 apparently healthy civil servants participating in the Paris Prospective Study I
Comparison
Highest tertile of heart rate increase during… vs Lowest tertile of heart rate increase during…
Design
Cohort
Follow-up
23 years
Authors
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May aid SCD risk stratification in stress testing; leaves open whether mental stress reactivity is causal or modifiable in healthy adults.
Cohort (n=7,746)
Does a large heart rate increase during mild mental stress predict sudden cardiac death in apparently healthy individuals?
Relative Risk: 2.09 (95% CI 1.13–3.86)
An excessive heart rate increase during mild mental stress before an exercise test is an independent predictor of long-term risk for sudden cardiac death in apparently healthy individuals.
Jouven et al. (2009) conducted a cohort in Apparently healthy individuals (n=7,746). Heart rate increase during mild mental stress vs. Lowest tertile of heart rate increase was evaluated on Sudden cardiac death (RR 2.09, 95% CI 1.13-3.86). A large heart rate increase during mild mental stress before an exercise test predicted a higher long-term risk of sudden cardiac death (RR 2.09; 95% CI 1.13-3.86).
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