Key result
Elevated resting heart rate was an independent risk factor for sudden death in middle-aged men, with the highest quintile having a 3.8-fold higher crude risk than the lowest (adjusted P=0.03).
Why the study?
Does an elevated resting heart rate predict sudden death in middle-aged men without known ischemic heart disease?
Population
7,079 middle-aged men (aged 42-53 years) without known ischemic heart disease
Comparison
Elevated resting heart rate (highest quintile) vs Lower resting heart rate (lowest quintile)
Design
Cohort
Follow-up
average 23 years
Authors
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May aid sudden death risk stratification in middle-aged men; leaves open whether rate reduction alters outcomes.
Cohort (n=7,079)
Does an elevated resting heart rate predict sudden death in middle-aged men without known ischemic heart disease?
Effect estimate: RR 3.8
p-value: p=0.03
An elevated resting heart rate is an independent, long-term predictor of sudden death in middle-aged men without prior ischemic heart disease.
Xavier Jouven (2001) conducted a cohort in Middle-aged men (n=7,079). Elevated resting heart rate vs. Lowest quintile of resting heart rate was evaluated on Sudden death (RR 3.8, p=0.03). Elevated resting heart rate was an independent risk factor for sudden death in middle-aged men, with the highest quintile having a 3.8-fold higher crude risk than the lowest (adjusted P=0.03).
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