Key result
Greater intrathoracic fluid congestion (OptiVol index >60) was associated with increased atrial tachyarrhythmia frequency compared to an index <40 (P=0.0342).
Why the study?
Is worsening pulmonary congestion (measured by OptiVol index) associated with increased atrial tachyarrhythmia frequency in patients with left ventricular dysfunction?
Population
59 patients with left ventricular systolic dysfunction and OptiVol index-capable implantable…
Comparison
Assessment of intrathoracic fluid status via… vs Comparison across OI levels
Design
Cohort
Follow-up
mean 3.8 visits per patient
Authors
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Supports congestion monitoring in LV dysfunction; hypothesis-generating and leaves causal direction open for trials.
Observational (n=59)
Is worsening pulmonary congestion (measured by OptiVol index) associated with increased atrial tachyarrhythmia frequency in patients with left ventricular dysfunction?
p-value: p=0.0342
Worsening pulmonary congestion is associated with increased atrial tachyarrhythmia frequency, and AT events may frequently trigger episodic pulmonary congestion in patients with LV dysfunction.
Jhanjee et al. (2009) conducted an observational in Left ventricular systolic dysfunction (n=59). Intrathoracic fluid congestion (OptiVol index >60) vs. OptiVol index <40 was evaluated on Atrial tachyarrhythmia frequency (percent of patient visits with at least 1 episode of AT since previous device interrogation) (p=0.0342). Greater intrathoracic fluid congestion (OptiVol index >60) was associated with increased atrial tachyarrhythmia frequency compared to an index <40 (P=0.0342).
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