Key result
In idealized coronary artery models, a degree of stenosis greater than 50% resulted in more disturbed fluid dynamics downstream, potentially increasing the risk of atherogenesis.
A multiphase mixture-theory model demonstrates that coronary stenosis >50% leads to significantly disturbed downstream fluid dynamics, potentially promoting atherogenesis.
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Suggests post-stenotic flow may promote atherogenesis; leaves open human outcome prediction.
Buradi et al. (2018) studied Coronary artery stenosis. Degree of stenosis severity vs. Lesser degrees of stenosis was evaluated on Wall shear stress (WSS) based hemodynamic descriptors. In idealized coronary artery models, a degree of stenosis greater than 50% resulted in more disturbed fluid dynamics downstream, potentially increasing the risk of atherogenesis.
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