Key result
Serotonin syndrome is a potentially serious adverse drug reaction caused by excess serotonin, with an estimated incidence of 0.5 to 0.9 cases per 1000 patient-months of treatment in general practice.
Population
Patients at risk of or presenting with serotonin syndrome
Design
Review
Loading...
Warrants vigilance for serotonergic combinations in practice; extends incidence estimates but leaves prospective validation open.
Serotonin syndrome is a potentially serious, predictable adverse drug reaction requiring prescriber vigilance regarding serotonergic drug combinations and CYP450 interactions.
A 2015 study conducted a review in Serotonin syndrome. Serotonergic agents was evaluated. Serotonin syndrome is a potentially serious adverse drug reaction caused by excess serotonin, with an estimated incidence of 0.5 to 0.9 cases per 1000 patient-months of treatment in general practice.