Key result
Brain natriuretic peptide accurately discriminated congenital heart disease from controls (AUC 0.918 in neonates) and its levels independently predicted intubation time after cardiac surgery.
Why the study?
Does brain natriuretic peptide measurement predict intubation time in neonates and children undergoing surgery for congenital heart disease?
Observational (n=772)
No
Does brain natriuretic peptide measurement predict intubation time in neonates and children undergoing surgery for congenital heart disease?
Brain natriuretic peptide demonstrates good diagnostic and prognostic accuracy in pediatric congenital heart surgery, but its baseline levels and response to surgical stress differ significantly between neonates and older children.
May aid risk stratification after pediatric congenital heart surgery; hypothesis-generating and requires prospective validation.
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Cantinotti et al. (2013) conducted an observational in Congenital heart disease (n=772). Brain natriuretic peptide (BNP) vs. Healthy controls was evaluated on Intubation time. Brain natriuretic peptide accurately discriminated congenital heart disease from controls (AUC 0.918 in neonates) and its levels independently predicted intubation time after cardiac surgery.
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