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May 1, 2010Congenital Heart DiseaseOpen Access

B-type Natriuretic Peptide: Perioperative Patterns in Congenital Heart Disease

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Population

105 children with congenital heart disease undergoing surgical repair, and 102 controls without…

Design

Case_series, blinded

Follow-up

perioperative/hospitalization

Authors

MNMatthew NiednerUniversity of MichiganJFJennifer L. FoleyRady Children's Hospital-San DiegoRRRobert H. RiffenburghSan Diego State University

Discussion

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Implication

BNP may aid postoperative risk assessment in pediatric CHD; case-report data leave open standardized thresholds amid age and lesion variation.

Structured PICO

P
Population
105 children with congenital heart disease (CHD) undergoing surgical repair, and 102 controls without cardiopulmonary disease (neonatal and non-neonatal).
C
Comparator
Controls without cardiopulmonary disease, and internal comparisons (neonates vs. non-neonates, biventricular vs. Fontan palliations)
O
Outcome
Perioperative BNP levels and their correlation with postoperative outcomes (inotropic requirement, lengths of open chest, ventilation, ICU stay, and hospitalization)surrogate

Perioperative BNP levels in children undergoing CHD repair correlate with illness severity and therapy duration, but exhibit substantial age and lesion-dependent variation that limits their utility as isolated point-of-care measures.

Cite This Study

Niedner et al. (2010) studied this question.

synapsesocial.com/papers/6a81d3f771edfdad573c8d78https://doi.org/10.1111/j.1747-0803.2010.00396.x

Topics

Congenital heart disease adults
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