Key result
Medical and surgical treatments significantly decreased plasma BNP levels in children with pulmonary arterial hypertension (981 to 26 pg/mL) and univentricular CHD (109 to 70 pg/mL; both p<0.05).
Why the study?
Do medical or surgical treatments reduce plasma BNP levels in children with heart disease?
Observational (n=522)
No
Do medical or surgical treatments reduce plasma BNP levels in children with heart disease?
Plasma BNP levels are elevated in children with heart disease and significantly decrease following medical or surgical treatment, serving as a useful monitoring parameter.
No takes yet. Share an insight, caveat, or question.
Supports BNP monitoring in treated pediatric PAH and univentricular CHD; hypothesis-generating for outcome impact.
Knirsch et al. (2011) conducted an observational in Heart disease (n=522). Medical or surgical treatment vs. Before treatment was evaluated on Plasma B-type natriuretic peptide (BNP) levels. Medical and surgical treatments significantly decreased plasma BNP levels in children with pulmonary arterial hypertension (981 to 26 pg/mL) and univentricular CHD (109 to 70 pg/mL; both p<0.05).
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