Key result
Renal replacement therapy did not increase the frequency or grade of premature ventricular beats, with arrhythmia incidence primarily dependent on preexisting coronary artery disease.
Why the study?
Does renal replacement therapy increase the frequency and grade of ventricular arrhythmias in patients with or without coronary artery disease?
Population
18 patients on maintenance renal replacement therapy, comprising 10 patients and 8 patients with confirmed…
Comparison
Sequential treatment with 8 different renal… vs Periods before and after renal replacement…
Design
Cohort
Follow-up
192 hours per patient
Authors
Loading...
Supports deferring arrhythmia surveillance at RRT initiation absent CAD; leaves open causal confirmation in prospective trials.
Does renal replacement therapy increase the frequency and grade of ventricular arrhythmias in patients with or without coronary artery disease?
Renal replacement therapy does not acutely increase the risk of ventricular arrhythmias in patients not taking digitalis, with arrhythmia incidence primarily driven by underlying coronary artery disease.
Wizemann et al. (2008) studied End-stage renal disease requiring maintenance renal replacement therapy (n=18). Renal replacement therapy (8 different methods including hemodialysis, hemofiltration, hemodiafiltration, and ultrafiltration) vs. Periods before and after therapy was evaluated on Frequency and grade of premature ventricular depolarizations. Renal replacement therapy did not increase the frequency or grade of premature ventricular beats, with arrhythmia incidence primarily dependent on preexisting coronary artery disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: