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December 15, 1992American Journal of Epidemiology

Acute Hemorrhagic Conjunctivitis Due to Enterovirus 70 in American Samoa: Serum-neutralizing Antibodies and Sex-specific Protection

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Key result

During an enterovirus 70 outbreak, the overall attack rate was 58%, with women aged 21-40 years experiencing higher attack rates than men of the same age (66% vs. 49%).

Population

1,095 individuals from 134 households on the island of Tutuila, American Samoa, surveyed during an outbreak…

Design

Cross-sectional

Authors

CBCaryn BernCenters for Disease Control and PreventionMPMark A. PallanschNorthwestern UniversityHGHoward E. GaryCenter for Global Health

Discussion

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Implication

May indicate higher outbreak vulnerability in women of childbearing age; leaves open confirmation of sex-specific risks in prospective studies.

Study Design

Type

Cross-Sectional (n=1,095)

Multicenter

No

Structured PICO

P
Population
1,095 individuals from 134 households surveyed during an outbreak of acute hemorrhagic conjunctivitis due to enterovirus 70 in American Samoa.
O
Outcome
Attack rates of acute hemorrhagic conjunctivitis

Main Result

Absolute Event Rate: 66% vs 49%

Enterovirus 70 can cause large outbreaks even in previously exposed populations, with only partial protection from previous infection and higher attack rates in young children and women of childbearing age.

Cite This Study

Bern et al. (1992) conducted a cross-sectional in Acute hemorrhagic conjunctivitis (n=1,095). Female sex (aged 21-40 years) vs. Male sex (aged 21-40 years) was evaluated on Acute hemorrhagic conjunctivitis attack rate. During an enterovirus 70 outbreak, the overall attack rate was 58%, with women aged 21-40 years experiencing higher attack rates than men of the same age (66% vs. 49%).

synapsesocial.com/papers/6a9cec513a657474307bea3ehttps://doi.org/10.1093/oxfordjournals.aje.a116471
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute Hemorrhagic Conjunctivitis Caused by Enterovirus Type 70: An Epidemic in American Samoa *1985 · 18 citations
  2. 2AN EPIDEMIC OF ACUTE HEMORRHAGIC CONJUNCTIVITIS IN AMERICAN SAMOA CAUSED BY COXSACKIEVIRUS A24 VARIANT1989 · 24 citations
  3. 3SEROSURVEY FOR “ACUTE HEMORRHAGIC CONJUNCTIVITIS” VIRUS (ENTEROVIRUS 70) ANTIBODIES IN THE SOUTHEASTERN UNITED STATES, WITH REVIEW OF THE LITERATURE AND SOME EPIDEMIOLOGIC IMPLICATIONS11975 · 44 citations
  4. 4Acute Hemorrhagic Conjunctivitis in Southeast Asian Refugees Arriving in the United States—Isolation of Enterovirus 701982 · 8 citations
  5. 5Acute haemorrhagic conjunctivitis: Seroepidemiology of coxsackievirus A24 variant and enterovirus 70 in Singapore1990 · 28 citations