Key result
Absent diastolic flow in the umbilical artery predicted poor short-term prognosis in fetuses with congenital heart disease, with 100% (10/10) dying in utero, neonatally, or being aborted.
Why the study?
Does absent diastolic flow in the umbilical artery predict poor short-term prognosis in fetuses with congenital heart disease?
Population
244 pregnancies referred for fetal echocardiography, including 152 normal pregnancies >20 weeks gestation…
Comparison
Pulsed Doppler ultrasound assessment of… vs Normal umbilical blood flow
Design
Cohort
Follow-up
Up to neonatal period or in utero death
Authors
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May inform fetal CHD counseling; leaves open prospective validation before guiding decisions.
Observational (n=244)
Does absent diastolic flow in the umbilical artery predict poor short-term prognosis in fetuses with congenital heart disease?
Absent diastolic flow in the umbilical artery is a strong predictor of short-term mortality in fetuses with congenital heart disease.
Al-Gazali et al. (1987) conducted an observational in Fetal cardiac abnormality (n=244). Absent diastolic flow in the umbilical artery vs. Normal umbilical blood flow was evaluated on Short-term prognosis (fetal death, neonatal death, or abortion). Absent diastolic flow in the umbilical artery predicted poor short-term prognosis in fetuses with congenital heart disease, with 100% (10/10) dying in utero, neonatally, or being aborted.
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