Key result
Heparin dosing requires modification in severe obesity, factor Xa inhibitors are a safe option, and routine use of inferior vena cava filters lacks evidence in obese surgical patients.
Why the study?
Surgeries in obese patients have increased significantly, leading to more perioperative embolic complications, which present pharmacological challenges and require sufficient evidence to ensure safety with minimal risk.
Does thromboprophylaxis prevent perioperative embolic events in obese patients undergoing surgery?
Population
Obese patients undergoing surgery
Design
Literature review
Authors
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Dosing uncertainties for heparins and factor Xa inhibitors persist in obese surgical patients; leaves open the need for prospective trials to guide practice.
Does thromboprophylaxis prevent perioperative embolic events in obese patients undergoing surgery?
This narrative review summarizes current evidence and challenges regarding dosing, timing, and methods of thromboprophylaxis in obese surgical patients.
Carreto et al. (2025) conducted a review in Obesity requiring surgery. Thromboprophylaxis strategies was evaluated. Heparin dosing requires modification in severe obesity, factor Xa inhibitors are a safe option, and routine use of inferior vena cava filters lacks evidence in obese surgical patients.
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