Key result
Obesity increases the risk of postoperative thrombosis after lower limb arthroplasty, yet current guidelines lack specific thromboprophylaxis dosing recommendations for this population.
Why the study?
Patients with obesity face increased venous thromboembolism risk following total joint arthroplasty, but clear dosing evidence and specific guideline recommendations for thromboprophylaxis in this population are lacking.
What is the optimal dosing of pharmacological thromboprophylaxis to prevent venous thromboembolism in patients with obesity undergoing lower limb arthroplasty?
Population
Patients with obesity undergoing major lower limb orthopaedic surgery
Design
Literature review
Authors
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Calls for individualized VTE risk assessment in obese arthroplasty patients; leaves open optimal thromboprophylaxis dosing for prospective trials.
What is the optimal dosing of pharmacological thromboprophylaxis to prevent venous thromboembolism in patients with obesity undergoing lower limb arthroplasty?
This review highlights the lack of specific guideline recommendations for thromboprophylaxis dosing in obese patients undergoing lower limb arthroplasty, emphasizing the need for individualized risk assessment.
Gurunathan et al. (2022) conducted a review in Venous thromboembolism after major lower limb orthopaedic surgery in obesity. Obesity was evaluated. Obesity increases the risk of postoperative thrombosis after lower limb arthroplasty, yet current guidelines lack specific thromboprophylaxis dosing recommendations for this population.
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